IN THE EARLY STAGES OF GUILLAIN-BARRE SYNDROME, GANGLIOSIDES (GM1 AUTOANTIBODIES AND GM 1) IN THE BLOOD SERUM
Abstract
In the last two decades, patients with GBS have shown variability in the course of the disease and its outcomes, despite timely specific therapy (plasmapheresis or class G immunoglobulins) In this regard, there is a need to create a system for predicting the condition of patients for a year from the moment of the appearance of the first clinical symptoms. The percentage of delayed diagnosis of the disease remains quite high, and the ambiguity of pathogenetic mechanisms makes it difficult to choose an adequate therapy. Mortality in GBS is 5-10% and a number of patients (16%) have severe residual manifestations of the disease that limit their medical and social rehabilitation.
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