BIONANOTEXNOLOGIYADAN FOYDALANIB,SUYAK TO’QIMASINI TIKLASH
Keywords:
sun’iy suyak,.ESHF, IMO, EO, terapiya, QKB,gistologik tajribalar;Abstract
Tibbiyotda biotexnologiyaning asosiy vazifalaridan biri zamonaviy implantlar uchun mos keluvchi materiallarni izlash va ishlab chiqishdir. Bunda olimlarga tirik organizmlar va ularning elementlari yordam beradi, ular yordamida ular shikastlangan to'qimalarni va hatto organlarni tiklashi mumkin.Shunday qilib, olimlar yaqinda suyak to'qimasini tiklash uchun gen faollashtirilgan materialni ishlab chiqishga muvaffaq bo'lishdi. Bu hozirgacha tibbiy amaliyotda qo'llanilgan dunyodagi yagona bunday materialdir.
References
Wegst UG, Bai H, Saiz E, Tomsia AP, Ritchie RO. Bioinspired structural materials. Nat Mater. 2015;14(1):23–36.
Article CAS PubMed Google Scholar
Lopes D, Martins-Cruz C, Oliveira MB, Mano JF. Bone physiology as inspiration for tissue regenerative therapies. Biomaterials. 2018;185:240–75.
Article CAS PubMed PubMed Central Google Scholar
Morrison SJ, Scadden DT. The bone marrow niche for haematopoietic stem cells. Nature. 2014;505(7483):327–34.
Article CAS PubMed PubMed Central Google Scholar
Phukan R, Herzog T, Boland PJ, Healey J, Rose P, Sim FH, et al. How does the level of sacral resection for primary malignant bone tumors affect physical and mental health, pain, mobility, incontinence, and sexual function? Clin Orthop Relat Res. 2016;474(3):687–96.
Article PubMed Google Scholar
Majidinia M, Sadeghpour A, Yousefi B. The roles of signaling pathways in bone repair and regeneration. J Cell Physiol. 2018;233(4):2937–48.
Article CAS PubMed Google Scholar
De Melo PD, Habibovic P. Biomineralization-inspired material design for bone regeneration. Adv Healthc Mater. 2018;7(22):e1800700.
Article CAS Google Scholar
Schemitsch EH. Size matters: defining critical in bone defect size! J Orthop Trauma. 2017;31(Suppl 5):S20–S2.
Article PubMed Google Scholar
Habibovic P. Strategic directions in osteoinduction and biomimetics. Tissue Eng Part A. 2017;23(23–24):1295–6.
Article PubMed Google Scholar
Pape HC, Evans A, Kobbe P. Autologous bone graft: properties and techniques. J Orthop Trauma. 2010;24(Suppl 1):S36–40.
Article PubMed Google Scholar
