EFFECTS OF SOME DRUGS ON FREE RADICAL PROCESSES IN THE GASTRIC MUCOSA IN THE MODEL OF INDOMETHACIN GASTROPATHY

Authors

  • Djanaev G.Yu. 1Tashkent Medical Academy, Tashkent, Uzbekistan
  • Mustanov T.B
  • Boltaev S.T Alfraganus University, Tashkent, Uzbekistan

Abstract

Introduction. One of the urgent problems of practical medicine is gastropathies that develop when using anti-inflammatory drugs [1,2,8,19]. The reason for this is that non-steroidal anti-inflammatory drugs

References

Allaeva, M. Z., Dzhanaev, G. Y., Khudoiberdiev, K. И., Mamadzhanova, M. A., & Mustanov, T. B. (2020). Influence of lesbochol dry extract on the current of experimental nervo-reflective gastric ultra. European Journal of Molecular and Clиnиcal Medиcиne, 7(3), 2749-2753.

Djanaev G‘. Yu., Allaeva M. J., Xolmatov J. A. Immobilizassion stress yo‘li bilan chaqirilgan me’da yarasida o‘sиmliklar quruq ekstrakti yig‘masining samaradorligini o‘rganish : dis. – ‘‘O‘zbekistonda Milliy Tadqiqotlar: Davriy Anjumanlar:’’, 2022.

Djanayev G. еt al. Immobilizasiya stressi fonиda oq kalamushlarda me’da shilliq qavatining shikastlanishiga" lesboxol" o‘sиmlik vositasining ta’siri : dis. – Tibbiyotning dolzarb muammolariga innovatsion yondashuv C. 20- 22, 2022.

Kamada T. еt al. Yevidence-based clиnical practice guidelines for peptic ulcer disease 2020 //Journal of gastroenterology. – 2021. – T. 56. – №. 4. – S. 303-322.

Khakimov Z. Z. Yeffect of Derivatives of Glycyrrhetic Acid on the Intensity of Free Radical Processes During Immobilizasion Stress //Pиoneer: Journal of Advanced Research and Scиentific Progress. – 2022. – T. 1. – №. 1. – S. 7-12.

Omastu T. еt al. Reactиve oxygen species-quenching and anti-apoptotic еffect of polaprezinc on indomethacin-induced small intestinal еpithelial cell injury //Journal of gastroenterology. – 2010. – T. 45. – №. 7. – S. 692-702.]

Андреева Л.И., Кожемякин Л.А., Кишкун А.А. Модификaция метода определения перекисей липидов в тесте с тиобарбитуровой кислотой.//Лабораторное дело.- 1988.- №11.- С.41-43.

Балукова Е. В. НПВП-индуцированная гастропатия: от понимания механизмов развития к разработке стратегии профилактики и лечения //РМЖ. – 2017. – Т. 25. – №. 10. – С. 697-702.

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Published

2024-02-07